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Clinical Trial News

Chimeric mouse study 'could have prevented human deaths in 1993 drug trial'

Should 'humanized' mice be used routinely in preclinical drug trials? A study finds that adoption of this animal test could have saved human lives in a fatal clinical trial.

Chinese herbal remedy 'just as effective as methotrexate against arthritis'

A Chinese herbal remedy - Triptergium wilfordii Hook F - is just as effective for treating symptoms of rheumatoid arthritis than commonly used drug methotrexate, a study suggests.

Interferon-free therapy for hepatitis C 'cured' 90% of patients

An experimental oral therapy for hepatitis C took only 12 weeks to cure 90% of patients with liver cirrhosis and was found safe for those who could not have interferon.

Indoor rabbits could be deficient in vitamin D

Rabbits that remain indoors may suffer from a lack of vitamin D, researchers report in a new study.

Moffitt Cancer Center begins Phase I clinical trial of new immunotherapy

Moffitt Cancer Center has initiated a phase I clinical trial for a new immunotherapy drug, ID-G305, made by Immune Design.

Gilead announces results from study of Sovaldi® for retreatment of chronic hepatitis C in patients not cured with prior antiviral therapy

Gilead Sciences, Inc. has announced results from an open-label clinical trial (Study GS-US-334-0109) evaluating once-daily Sovaldi® (sofosbuvir) 400 mg tablets for the retreatment of chronic...

Genkyotex's GKT137831 found to reverse fibrosis and improve survival in a model of persistent lung fibrosis

Genkyotex, the leading developer of selective NOX enzyme inhibitors, has announced the publication of data showing that GKT137831, a first in class NOX1 and 4 inhibitor, was able to reverse lung...

Phase 3 results announced for paediatric study of investigational therapy Eloctate (TM) for haemophilia A

Biogen Idec and Swedish Orphan Biovitrum AB (Sobi) have released positive top-line results of the Kids A-LONG Phase 3 clinical study that evaluated the safety and efficacy of Eloctate(TM), an...

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