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Clinical Trial News

New drug '20% more effective than ACE inhibitors' for treating heart failure

A new study claims that an experimental drug called LCZ696 is 20% more effective than ACE inhibitors in reducing heart failure-related hospitalizations and deaths.

What is a systematic review of medical research?

Systematic reviews and meta-analyses are loved by people issuing guidelines on the best medical treatments. Find out why they are so powerful, but also about their disadvantages.

New report shows that HPV vaccine trials can be significantly shortened

A new report from a Working Group convened by the International Agency for Research on Cancer (IARC), the specialized cancer agency of the World Health Organization, and the United States National...

Study questions generalizability of findings of cardiovascular trials for heart attack patients

An analysis of a cardiovascular registry finds that of clinical trials that included heart attack patients, participation among eligible patients was infrequent and has been declining, and trial...

First clinical trial for new skin wound-healing compound is a success

Virginia Tech Carilion Research Institute scientist Robert Gourdie developed a wound-healing peptide while researching how electrical signals trigger heartbeats.

Palbociclib expanded access program now open to eligible U.S. patients with HR+, HER2- advanced breast cancer

Pfizer Inc. has announced that the company has initiated a multi-center, open-label expanded access program (EAP) in the United States for the investigational CDK 4/6 inhibitor, palbociclib.

Clinical trials of unscientific, 'alternative' medicines denounced by experts

Experts writing in the Cell Press journal Trends in Molecular Medicine call for an end to clinical trials of "highly implausible treatments" such as homeopathy and reiki.

Commercialization delayed by early bottlenecks in developing biopharmaceutical products

An analysis of patented university inventions licensed to biotechnology firms has revealed early bottlenecks on the path to commercialization.

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